Melbourne tram route 3 is a tram route on the Melbourne tramway network serving the city of Melbourne in Victoria, Australia. Operated by Yarra Trams, the route is coloured light blue and extends from Melbourne University to East Malvern over 14.9-kilometre (9.3 mi) of double track via Swanston Street, St Kilda Road and Caulfield. It is serviced out of Glenhuntly depot utilising Z and B class trams. Until October 2023, route 3 operated as 3a on weekends, diverting via St Kilda Beach.
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{"type":"standard","title":"Barrier-to-autointegration factor","displaytitle":"Barrier-to-autointegration factor","namespace":{"id":0,"text":""},"wikibase_item":"Q24772819","titles":{"canonical":"Barrier-to-autointegration_factor","normalized":"Barrier-to-autointegration factor","display":"Barrier-to-autointegration factor"},"pageid":32158106,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/03/PDB_1ci4_EBI.jpg/330px-PDB_1ci4_EBI.jpg","width":320,"height":240},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/0/03/PDB_1ci4_EBI.jpg","width":800,"height":600},"lang":"en","dir":"ltr","revision":"1186968588","tid":"87aa13b6-8c7b-11ee-b1aa-0c2c4e0efd46","timestamp":"2023-11-26T16:47:48Z","description":"Family of proteins","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Barrier-to-autointegration_factor","revisions":"https://en.wikipedia.org/wiki/Barrier-to-autointegration_factor?action=history","edit":"https://en.wikipedia.org/wiki/Barrier-to-autointegration_factor?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Barrier-to-autointegration_factor"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Barrier-to-autointegration_factor","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Barrier-to-autointegration_factor","edit":"https://en.m.wikipedia.org/wiki/Barrier-to-autointegration_factor?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Barrier-to-autointegration_factor"}},"extract":"In molecular biology, barrier-to-autointegration factor (BAF) is a family of essential proteins that is highly conserved in metazoan evolution, and which may act as DNA-bridging proteins. BAF binds directly to double-stranded DNA, to transcription activators, and to inner nuclear membrane proteins, including lamin A filaments that anchor nuclear pore complexes in place, and nuclear LEM-domain proteins that bind to lamin filaments and chromatin. New findings suggest that BAF has structural roles in nuclear assembly and chromatin organization, represses gene expression and might interlink chromatin structure, nuclear architecture and gene regulation in metazoans.","extract_html":"
In molecular biology, barrier-to-autointegration factor (BAF) is a family of essential proteins that is highly conserved in metazoan evolution, and which may act as DNA-bridging proteins. BAF binds directly to double-stranded DNA, to transcription activators, and to inner nuclear membrane proteins, including lamin A filaments that anchor nuclear pore complexes in place, and nuclear LEM-domain proteins that bind to lamin filaments and chromatin. New findings suggest that BAF has structural roles in nuclear assembly and chromatin organization, represses gene expression and might interlink chromatin structure, nuclear architecture and gene regulation in metazoans.
"}